PR1MA™  Paromomycin Sulfate

CAS Number: 1263-89-4
Molecular Weight: 615.6
Chemical Formula: C₂₃H₄₅N₅O₁₄ • H₂SO₄
Solubility: Water
Storage Temp: Room Temperature

Aminoglycoside antibiotic with mode of action similar to Kanamycin and Neomycin. Used as a selective agent for the incorporation of the NPT II (APH3') gene in plant tissue. Plant culture tested.

Research or further manufacturing use only, not for food or drug use.

• Appearance: White to Off White Powder
• Assay: ≥ 675 U/mg
• Identification: Conforms
• Loss on Drying: ≤ 5.0 %
• pH 3.0% Solution @25^oC: 5.0 -7.5
• Specific Optical Rotation: +50.0 - +55.0°

PR1MA™ Nourseothricin Sulfate [NTC] [clonNAT] [Streptothricin Sulfate]

Common Name: [NTC] [clonNAT] [Streptothricin Sulfate]
CAS Number: 96736-11-7
Solubility: Water
Storage Temp: 2-8°C

Dihydrogen sulfate form of the weekly basic antibiotic Nourseothricin consisting of components F, E and D. Effective against gram negative and gram positive bacteria. Also effective against mycobacteria, mycoplasms, protozoa, yeasts, viruses and plants. Commonly used as a selection agent for recombinant yeast strains.

Research or further manufacturing use only, not for food or drug use.

• Appearance: White Powder
• Carbon (C): Report %
• Hydrogen (H): Report %
• Nitrogen (N): Report %
• Purity (HPLC): ≥ 85 %
• Sulfur (S): Report %

PR1MA™  Bacitracin

CAS Number: 1405-87-4
Molecular Weight: 1422.69
Chemical Formula: C₆₆H₁₀₃N₁₇O₁₆ S
Solubility: Water, Ethanol, and Methanol
Storage Temp: 2-8°C

Interferes with bacterial cell wall synthesis. Active against gram positive bacteria. Toxic to plant cells.

Research or further manufacturing use only, not for food or drug use.

• Appearance: White to pale buff powder
• Identification: Pass test
• pH: 5.5 - 7.5
• Loss on Drying: ≤ 5.0 %
• Residue on Ignition: ≤ 0.5 %
• Bacitracin A: ≥ 40.0 %
• SUM of bacitracin A, B1, B2 and B3: ≥ 70.0 %
• Limit of early eluting peptides: ≤ 20.0 %
• Limit of Bacitracin F: ≤ 6.0 %
• Microbial Assay (Dried Basis): ≥ 65.0 IU / mg
• Heavy Metals : ≤ 30 ppm
• Total Viable Aerobic Count: ≤ 100 CFU/g
• Particle Size (< 20 µm by volume): ≥ 99.0 %
• Crystallinity : Pass
• Appearance of Solution: Clear, colorless to slight hazy yellow
• Source: Bacillus Licheniformis
• Non Animal Origin: Non Animal Origin
• Grade: USP
• Country of Origin : Report

PR1MA™ bis-TRIS [bis-(2-hydroxyethyl)aminotris(hydroxymethyl)methane]

Common Name: bis(2-Hydroxyethyl)aminotris (hydroxymethyl)methane
CAS Number: 6976-37-0
Molecular Weight: 209.2
Chemical Formula: C₈H₁₉NO₅
Solubility: Water
Storage Temp: Room Temperature

Research or further manufacturing use only, not for food or drug use.

• Appearance: White crystalline powder
• Assay: ≥ 99.0 %
• Identification (IR): Matches reference
• Melting Point: Report ^oC
• pH, 1.0M Aqueous solution @25ºC: 9.5 - 11.0
• pKa @ 20°C: 6.0 - 7.0
• Solubility: Complete and clear
• UV Absorbance @280nm, 1.0 M in H₂O: ≤ 0.40

CAS Number: 1264-72-8
Molecular Weight: 2801.27
Chemical Formula: (C₅₂H₉₈N₁₆O₁₃ )₂ • 5(H₂SO₄)
Solubility: Water
Storage Temp: Short Term: 2-8°C; Long Term: -20°C

Active against gram negative bacteria. Potency approximately 20,000 units per milligram.

Research or further manufacturing use only, not for food or drug use.

• Appearance: White or almost white powder
• Arsenic (As): ≤ 2 ppm
• Heavy Metals : ≤ 20 ppm
• Identification: Conforms
• Loss on Drying: ≤ 3.5 %
• pH (1% in H₂O): 4.0 - 6.0
• Potency (Dried basis): ≥ 19000 µg/mg
• Solubility (50mg/ml in H₂O): Clear and light yellow solution
• Specific Rotation: -73 - -63 °
• Sulfate: 16.0 - 18.0 %
• Sulfated Ash: ≤ 1.0 %

PR1MA™  Polymixin B Sulfate

CAS Number: 1405-20-5
Molecular Weight: 1385.61
Chemical Formula: C₅₅H₉₆N₁₆O₁₃ • 2H₂SO₄
Solubility: Water
Storage Temp: 2-8°C

Mixture of sulfates of polypeptides from certain strains of Bacillus polymixa. Active against gram negative bacteria.

Research or further manufacturing use only, not for food or drug use.

• Appearance: White to Light Yellow Powder
• Identification: Pass Test
• pH (0.5% Solution): 5.0 - 7.5
• Loss on Drying: ≤ 7.0 %
• Single Impurity: ≤ 3.0 %
• Total impurities: ≤ 17.0 %
• Bacteria Colonies: ≤ 10/g
• Ecoli Colonies: Should not be found
• Fungi and Yeast colonies: ≤ 10/g
• Assay, HPLC (on dried basis) (Sum of polymxin B1,B2, B3 and B1-1): ≥ 80.0 %
• Assay, HPLC (on dried basis) (Polymyxin B3): ≤ 6.0 %
• Assay, HPLC (on dried basis) (Polymyxin B1-1): ≤ 15.0 %
• Assay (Dried Basis): ≥ 6000 U/mg
• Assay (Wet Basis): Report U/mg
• Non Animal Origin: Non Animal Origin
• Grade: USP
• Country of Origin: Report

PR1MA™  Spectinomycin Dihydrochloride Pentahydrate

CAS Number: 22189-32-8
Molecular Weight: 495.3
Chemical Formula: C₁₄H₂₄N₂O₇ • 2HCl • 5H₂O
Solubility: Water
Storage Temp: 2-8°C

Aminocyclitol antibiotic that inhibits protein synthesis. Cell culture tested.

Research or further manufacturing use only, not for food or drug use.

• Appearance: White or almost white, Slightly hygroscopic powder
• Identification: Pass Test
• pH @25 °C: 3.8 - 5.6
• Potency : ≥ 603 IU/mg
• Residue after Ignition: ≤ 1.0 %
• Solubility: Clear and colorless to light yellow
• Specific Rotation: +15 - +21 °
• Water (KF): 16.0 - 20.0 %

PR1MA™ Mitomycin C

CAS Number: 50-07-7
Molecular Weight: 334.3
Chemical Formula: C₁₅H₁₈N₄O₅
Solubility: Ethanol
Storage Temp: 2-8°C 

Antineoplastic antibiotic that acts as an alkylating agent after activation and also suppresses the synthesis of nucleic acids. A cell-cylce non specific agent, most active in the late G1 and early S phases.

WARNING! This product can expose you to Mitomycin-C, a chemical which is known to the State of California to cause cancer. For more information go to www.P65Warnings.ca.gov.

Research or further manufacturing use only, not for food or drug use.

• Appearance: Blue violet solid
• Identification (UV): Conforms
• Purity-HPLC (RP CH₃CN:H₂O-0-100%): ≥ 99.0 %
• Purity-HPLC (RP MEOH:H₂O-90-10): ≥ 98.0 %
• Purity-TLC (CH₂CL₂:MEOH- 9:1): ≥ 98.0 %
• Solubility (10 mg/ml MEOH): Clear Blue Solution

PR1MA™ DTT [DL-Dithiothreitol] (Cleland's Reagent)]

Common Name: [DL-Dithiothreitol] (Cleland's Reagent)]
CAS Number: 3483-12-3
Molecular Weight: 154.25
Chemical Formula: C₄H₁₀O₂S₂
Solubility: Water
Storage Temp: 2-8°C

Protective reagent for maintaining -SH groups in reduced state. DTT permeates the cell membrane, protecting protein sulfhydryls, thereby restoring enzyme activity lost by oxidation of the groups.

Research or further manufacturing use only, not for food or drug use.

• Appearance: A white free flowing powder, hygroscopic
• Solubility: Freely soluble in methanol, methylene chloride
• Clarity in water: 5% (w/v) solution in water is clear and colorless
• Identification by TLC: Rf value of the sample is comparable with that of the standard
• Melting Range: 37.0 - 44.0 °C
• Related Substance (UV Spectroscopy- Content of Oxidised DTT): 0.4 %
• Assay (By Iodimetry): ≥ 98.0 %
• Country of Origin: Report

PR1MA™  HEPES, Free Acid [N-(2-Hydroxyethyl) piperazine N'-(2-ethanesulfonic acid)]

Common Name: [N-(2-Hydroxyethyl) piperazine N'-(2-ethanesulfonic acid)]
CAS Number: 7365-45-9
Molecular Weight: 238.3
Chemical Formula: C₈H₁₈N₂O₄S
Solubility: Water
Storage Temp: Room Temperature

Zwitterionic N-substituted aminosulfonic acid buffer.

• pka (25°C): 7.5
• pH Range (Working): 6.8 - 8.2
• Heavy Metals: <0.001% Max

• Appearance: White Crystalline Powder
• Assay (Titration, dried basis): ≥ 99.5 %
• DNase, RNase, protease: Not Detected
• Endotoxin (0.2% Solution): ≤ 0.25 EU/ml
• Heavy Metals (as Pb): ≤ 0.001 %
• Identification (IR): Pass
• Iron (Fe): ≤ 0.0005 %
• Loss on Drying: ≤ 1.0 %
• pH (5% in water): 5.0 - 6.5
• pKa @ 20°C: 7.35 - 7.70
• Residue on Ignition: ≤ 0.1 %
• Solubility (1M Solution in Water ): Clear and Colorless Solution
• Sulfate: ≤ 0.05 %
• UV Absorbance (1M@260nm): ≤ 0.05
• UV Absorbance (1M@280nm): ≤ 0.05

PR1MA™ Puromycin Dihydrochloride

CAS Number: 58-58-2
Molecular Weight: 544.43
Chemical Formula: C₂₂H₂₉N₇O₅ • 2HCl
Solubility: Water
Storage Temp: -20°C

Amino nucleoside antibiotic allows the selection of cells expressing the pac gene. Inhibits the growth of gram-positive bacteria and various animal and insect cells.

Research or further manufacturing use only, not for food or drug use.

• Appearance: White to Off White Powder
• Identification (TLC): Conforms
• Melting Point: 168 - 182 ^oC
• Purity (HPLC): ≥ 98.0 %
• Solubility: Clear, colorless or light yellow solution
• Water (KF): ≤ 12.0 %

PR1MA™  Blasticidin S Hydrochloride Powder

CAS Number: 3513-03-9
Molecular Weight: 458.9
Chemical Formula: C₁₇H₂₆N₈O₅ • HCl
Solubility: Water
Storage Temp: -20°C

• Appearance: White Powder
• Endotoxin : ≤ 1.0 EU / mg
• Identification: Pass Test
• Potency: ≥ 850 ug / mg
• Purity (HPLC): ≥ 98.0 %
• Solubility: Clear, Slightly yellow solution at 5 mg / mL in water