PR1MA™ Expanded Surface Tissue Culture Treated Roller Bottles

Designed to maximize cell growth efficiency while saving valuable lab space.

Featuring a uniform hydrophilic surface, these ESRB bottles support consistent cell attachment and growth, making them ideal for a wide range of cell culture applications. Available in multiple sizes and cap configurations, including vented and non-vented options, these roller bottles provide flexibility for both open and closed systems.

• Increase productivity with larger surface areas
• Reduce handling time and repetitive tasks
• Optimize laboratory space with high-capacity bottle options
• Maintain consistent and reliable cell growth conditions

Main Attributes

• Expanded surface (ESRB) design maximizes cell culture area and efficiency
• Horizontal ribbing promotes more even cell exposure compared to vertical rib designs
• Tissue culture treated surface ensures a uniform hydrophilic surface for reliable cell attachment
• Large knurled caps for easy handling and secure grip
• Vented and non-vented cap options for application flexibility
• Medical-grade virgin polystyrene construction for consistent performance
• Easy-to-read black printed graduations for accurate measurement
• Sterile, individually bagged packaging for immediate use 

Available Configurations

• 1900 cm² Expanded Surface Roller Bottles
• Available with non-vented or vented caps
• Expanded surface design increases available growth area
• Vented cap option includes a 0.22 uM hydrophobic membrane for gas exchange in open systems
• 4250 cm² Expanded Surface Roller Bottles
• Designed for large-scale cell culture applications
• Provides the equivalent growth area of five standard 850 cm² bottles while using 40% less plastic
• Fits into roller apparatuses that accommodate two standard 850 cm² bottles

New Look, Same Reliable Product
 Now from PR1MA™ with Updated Part Numbers

PR1MA™ PC Erlenmeyer Flasks

Sterile, vent cap, polycarbonate flasks.

PR1MA™ PC Erlenmeyer Flasks are designed for reliable performance in mammalian suspension culture, as well as bacterial and yeast applications. Manufactured from medical-grade virgin polycarbonate (PC), these flasks combine durability with lightweight handling and are autoclavable from -80ºC to 121ºC, making them suitable for a range of laboratory workflows.

Available in both plain bottom and baffled bottom designs, these flasks provide flexibility depending on application needs. The vented caps feature a 0.22 uM hydrophobic membrane with an oversized vent area, enabling efficient gas exchange while reducing contamination risk. With pre-sterilized, single-use packaging, these flasks help maintain clean working conditions and simplify lab processes.

Main Attributes

• Designed for mammalian suspension culture, bacterial, and yeast applications
• Vented cap with 0.22 uM hydrophobic membrane for improved gas exchange
• Oversized vent area enhances aeration and performance
• Plain and baffled bottom options:
• Plain bottom for standard applications
• Baffled bottom improves vertical and circular movement for enhanced aeration
• Made from medical-grade virgin polycarbonate (PC)
• Autoclavable from -80ºC to 121ºC
• Lightweight plastic for safer, easier handling compared to glass
• Molded graduations and 1/3 fill line for accurate volume guidance
• Individually bagged and pre-sterilized for convenience and contamination control 

Benefits

• Supports consistent and efficient culture growth
• Improves aeration with baffled design options
• Reduces contamination risk with sterile, single-use packaging
• Easy handling and durability improve lab workflow efficiency

New Look, Same Reliable Product
 Now from PR1MA™ with Updated Part Numbers

PR1MA™ PC Erlenmeyer and Fernbach Flasks

Sterile, vented culture flasks.

PR1MA™ PC Erlenmeyer and Fernbach Flasks are designed for reliable performance in mammalian suspension culture, as well as bacterial and yeast applications. Available in 2 L Erlenmeyer and 2 L and 3 L Fernbach configurations, these flasks provide flexible options to support a variety of laboratory workflows. Each flask is pre-sterilized and features a 70 mm wide opening, allowing for easy filling and dispensing.

Equipped with vent caps featuring an oversized vent area, these flasks promote improved gas exchange for optimal culture conditions. Fernbach flasks offer an increased surface area-to-volume ratio, while baffled bottom options enhance mixing and aeration for more efficient cell growth and culture performance.

Main Attributes

• Designed for mammalian suspension culture, bacterial, and yeast applications
• Available in 2 L Erlenmeyer and 2 L / 3 L Fernbach flask formats
• 70 mm wide opening for easy handling, filling, and dispensing
• Pre-sterilized for convenience and immediate use
• Oversized vent cap area improves gas exchange
• Fernbach shape increases surface area for enhanced culture efficiency
• Baffled bottom options improve mixing, aeration, and culture movement 

Accessories

• 70 mm Replacement Caps (Sterile):
• Solid cap options
• Vent cap options with oversized vent area for improved gas exchange
• 2.0 uM Pore Size
• PTFE Membrane
• 50 mm Filter Diameter
• Transfer Assembly for 3 L Fernbach Flask (Sterile):
• Designed for aseptic transfer of materials
• Compatible with 3 L Fernbach flasks
• PR-FFVCPB-PC-3L
• PR-FFVCBB-PC-3L

Benefits

• Supports efficient and reproducible culture growth
• Enhances aeration and mixing for improved results
• Simplifies workflows with sterile, ready-to-use flasks
• Flexible configurations for varied lab applications

Same Reliable Product, Now with Updated Part Numbers

PR1MA™ Tissue Culture Treated Roller Bottles

Sterile, vented, and non-vented options.

PR1MA™ Tissue Culture Treated Roller Bottles are designed to deliver reliable and consistent performance for cell culture applications. With a uniform hydrophilic surface, these bottles promote optimal cell attachment and growth, making them ideal for a wide range of laboratory workflows. Available in 490 cm² and 850 cm² sizes with both vented and non-vented cap options, these roller bottles provide flexibility for closed and open system applications.

• Supports consistent and reproducible cell culture results
• Flexible options for different workflows and system requirements
• Easy handling and reliable performance in laboratory environments
• Multiple sizes to accommodate varying culture volumes 

Main Attributes

• Tissue culture treated surface provides a uniform hydrophilic environment for consistent cell attachment
• Large knurled caps ensure easy handling and secure grip
• Vented cap options designed for open system applications with 0.22 uM hydrophobic membrane
• Medical-grade virgin polystyrene construction ensures quality and consistency
• Easy-to-read black printed graduations for accurate measurement
• Sterile packaging in individual bags or bulk sterile bags for convenience and protection 

Available Configurations

• 490 cm² Roller Bottles
• Vented (PR-RBVC-490) and non-vented (PR-RBNVC-490) cap options
• Vented caps include a 0.22 uM hydrophobic membrane for gas exchange
• 850 cm² Roller Bottles
• Vented (PR-RBVC-850) and non-vented (PR-RBNVC-850) cap options
• Vented versions support open system culture with membrane filtration
• Available in bulk (PR-RBVC-850-40): 20 bottles per sterile vacuum bag with dual dust bag layers, 2 bags per case

PR1MA™ Non-Treated Roller Bottles

Non-treated roller bottles with sterile, non-vented cap.

PR1MA™ Non-Treated Roller Bottles are designed for reliable cell culture applications requiring non-treated surfaces. Manufactured from medical-grade virgin polystyrene, these roller bottles provide consistent performance and durability while maintaining sterility with individual packaging.

Main Attributes

• Non-treated surface ideal for suspension cultures or specialized cell applications
• Non-vented cap ensures a secure seal during use
• Large knurled cap provides easy handling and improved grip
• Medical-grade virgin polystyrene construction for consistency and quality
• Easy-to-read black printed graduations allow accurate volume measurement
• Individually bagged and sterile for immediate use in laboratory environments 

Cell Culture Guidelines

• Recommended seeding density: 1 x 10³ to 1 x 10⁵ cells/cm²
• Initial adhesion phase (first 24 to 48 hours):
• Rotation speed: 0.5 to 1.0 rpm
• For cells with lower adhesion:
• Rotation speed: 0.3 to 0.5 rpm

*Note: These parameters are general recommendations; optimize conditions based on specific cell lines.

Cell Harvesting Protocol

• Rinse the bottle twice with PBS
• Add a dissociation solution (e.g., trypsin), ensuring full coverage of the bottle interior and pleats
• Place the bottle in an incubator and rotate at 0.3 to 0.5 rpm for 5 to 10 minutes
• After cell detachment, add an equal volume of cell culture medium to neutralize trypsin
• Rotate the bottle to collect the cell suspension
• Remove cells by pouring or pipetting

Same Reliable Product, Now with Updated Part Numbers

PR1MA™ Untreated Multiwell Plates

Sterile, non-treated plates for cell culture.

PR1MA™ Untreated Multiwell Plates are designed for reliable performance in a wide range of cell culture and laboratory applications. These sterile, non-treated plates provide consistent results while offering user-friendly features that improve workflow efficiency and reduce contamination risks.

Main Attributes

• Alpha-numeric well labeling ensures simple and accurate identification of each well
• Raised well rims nest securely into the lid rings, helping reduce evaporation and minimize cross-contamination
• Lids with stacking capability enhance stability for handling and storage of multiple plates 

1 Well Plates

• Standard footprint matches traditional multiwell plates
• Ideal for high-volume and robotic screening of DNA libraries and manual plating
• Suitable for dot-blotting bacterial clones on 11.4 x 7.3 cm (4.5 x 2.875 In.) nylon membranes
• PR-NTPL-01

4 Well Plates

• Compact footprint with well size similar to 24 well plates
• Expanded spacing between wells helps reduce cross-contamination
• PR-NTPL-04

6, 12, 24, and 48 Well Plates

• Versatile formats for a wide range of cell culture workflows
• Designed for consistent performance and easy handling
• PR-NTPL-06
• PR-NTPL-12
• PR-NTPL-24
• PR-NTPL-48

96 Well Plates

• Available with or without lids for flexibility
• Choose round-bottom wells for efficient mixing or flat-bottom wells for standard applications
• Round-Bottom Well Options:
• PR-NTPRB-96
• PR-NTPRBL-96
• Flat-Bottom Well Options
• PR-NTP-96
• PR-NTPL-96
• Available in 5-pack option for sterile use
• PR-NTPL-96-5

384 Well Plates

• Ideal for automated workflows, including colorimetric assays and compound storage
• Designed for small-volume applications requiring precision and efficiency
• PR-NTPL-384

Same Reliable Product, Now with Updated Part Numbers

PR1MA™ Permeable Cell Culture Inserts

PR1MA™ Permeable Cell Culture Inserts are designed to support advanced cell culture applications by mimicking a variety of in vivo conditions. With multiple membrane materials and pore size options, these inserts provide flexibility for a wide range of applications, including angiogenesis, migration, chemotaxis experiments, cell interaction, and drug transport studies.

Insert design ensures proper centering within wells, allowing easy pipette access to the lower chamber while preventing unwanted wicking between the insert and side walls. Suspended above tissue culture-treated wells, these inserts enable efficient co-culture setups, allowing cells to grow both on the membrane and at the bottom of the well.

*Non-treated plates are sold separately.

For optimized performance, PET membranes offer excellent clarity for imaging and microscopy, while PC membranes provide superior cell attachment. This combination of versatility, ease of use, and reliable performance makes PR1MA™ inserts a valuable tool for cell culture workflows.

Main Attributes

• Designed to mimic in vivo conditions with 2 membrane materials and 4 pore sizes
• Centered insert design allows pipette access and prevents wicking
• Supports co-culture systems with growth on both membrane and well bottom
• Compatible with tissue culture-treated wells (non-treated plates sold separately)
• Clear PET membranes (0.1 uM and 0.4 uM) for enhanced cell visualization
• PC membranes for optimal cell attachment 

Pore Size Applications

• 0.1 uM and 0.4 uM: Ideal for cell-cell interaction and drug transport studies
• 3.0 uM and 8.0 uM: Ideal for angiogenesis, migration, and chemotaxis experiments

TPP Serological Pipets

TPP Serological Pipets are engineered to deliver precise and reliable liquid handling for cell culture, media preparation, and general laboratory use. Manufactured from premium-grade polystyrene, these pipets provide excellent optical transparency, smooth interiors to prevent cell hang-up, and high durability. Each pipet features highly visible bidirectional graduations with over-volume markings to ensure accurate dispensing and measurement.

For enhanced convenience, TPP offers a patented serological pipet with reservoir (US Patent 8,113,067B). This unique design expands liquid capacity without adding unnecessary length, improving ergonomics inside sterile hoods. The slim tip diameter allows easy access to narrow culture vessels while maintaining drop-free precision and robust performance.

All TPP Serological Pipets are DNase/RNase-free, endotoxin-tested, gamma sterilized, and individually wrapped for sterile assurance. With color-coded cotton plugs, ergonomic dispenser boxes, and compatibility with all standard pipet aids, TPP delivers accuracy, safety, and efficiency for every lab workflow.

Key Features

• Accurate, easy-to-read graduations with over-volume precision
• Smooth, transparent design prevents clumping and ensures clarity
• Patented reservoir option expands capacity without added length
• Ergonomic, slim tips fit narrow flasks and sterile hoods
• Durable, break-resistant polystyrene with color-coded identification
• Individually wrapped, sterile, and ready to use

Convenient Packaging

• Individually wrapped in paper/plastic or plastic/plastic blisters
• Color-coded, stackable dispenser boxes
• Options for single dispensing or bulk dispensing

Quality Assurance

• Manufactured with premium polystyrene for break resistance
• DNase/RNase-free, endotoxin level <0.1 EU/ml
• Sterilized by gamma irradiation   

Contact us today for free samples and discover how TPP’s innovative pipet designs can improve precision, ergonomics, and reliability in your lab.  
 

TPP Premium Conical 15 and 50 mL Centrifuge Tubes

TPP Premium Conical 15 and 50 mL Centrifuge Tubes are designed to meet the rigorous demands of modern laboratories. Manufactured from high-quality polypropylene (PP) and polystyrene (PS), these tubes are suitable for centrifugation, freezing, boiling, and long-term storage without cracking, buckling, or contamination.

Leak-proof screw caps with internal grooves ensure gas- and aerosol-tight sealing, while precise graduations allow for accurate sample measurement. The tubes feature a white writing surface for easy labeling on both the cap and side of the tube. Sterile, gamma-irradiated, and certified DNAse/RNAse-free, TPP PREMIUM Conical Tubes are perfect for applications ranging from reagent aliquoting to cell line cryopreservation and media filtration.

Key Features

• Freezing and boiling resistant; polypropylene tubes maintain integrity from -190°C to 100°C
• Buckle- and crack-proof during centrifugation
• Leak-proof screw caps with internal grooves, gas- and aerosol-tight
• Accurate graduations: 0.1 mL (15 mL) and 0.5 mL (50 mL)
• White writing surface for easy labeling on cap and tube
• Optimal material purity; no additives, biocides, or slip agents
• Outstanding optical clarity for easy sample observation
• Multiple application options: centrifugation, storage, filtration, cryopreservation

Applications

• Aliquoting and centrifuging reagents
• Long-term sample storage and cryopreservation
• Media filtration and storage
• Cell line freezing in isopropanol baths
• Minimizing contamination and maintaining sample integrity

Quality Assurance

• Sterile (gamma irradiated)
• Certified DNAse/RNAse, pyrogen, and heavy metal-free
• High optical clarity for reliable sample visualization

Contact us for free samples and discover how TPP Premium Conical Centrifuge Tubes

can ensure reliable sample integrity and streamline your lab workflows.

MTC™ Bio 15 mL Centrifuge Tubes

Leakproof, Durable, and Freezer-Safe Tubes for Everyday Lab Use.

These 15 mL centrifuge tubes are manufactured from premium-grade polypropylene (PP), offering superior clarity, strength, and chemical resistance for routine laboratory procedures. These tubes are designed for high-speed centrifugation, withstanding up to 12,000 x g, and are ideal for sample prep, pelleting, cell culture, and more.

Each tube features a frosted writing surface and flat-top screw cap for easy labeling and leak-resistant sealing. Select models offer a skirted (self-standing) base, allowing them to stand upright on the benchtop without a rack, perfect for hands-free use and enhanced workflow efficiency.

All 15 mL tubes are sterile and certified RNase-, DNase-, pyrogen-, and cytotoxin-free, ensuring the integrity of sensitive biological samples. Available in bags, or eco-friendly plastic racks for improved lab organization and storage.

Key Features

• Made of high-quality polypropylene for durability and clarity
• Withstands centrifugation up to 12,000 x g
• Leakproof to 95 kPa / 14 psi
• Freezer-safe down to -86°C
• Flat-top caps for easy labeling and secure closure
• Available in self-standing (skirted) or conical bottom
• Sterile, RNase, DNase, pyrogen, and cytotoxin-free
• Supplied bagged or in eco-plastic racks
• Compatible with standard 15 mL centrifuge rotors

Applications

• Sample collection and storage
• Cell culture and pelleting
• DNA/RNA isolation
• Clinical and diagnostic testing
• Freezing and centrifugation of biological fluids

Round Bottom Snap Cap Tubes

No more fumbling with caps for your tubes.

MTC Bio’s new round bottom snap cap culture/centrifuge tubes adopt the conveniences of popular 1.5 mL microcentrifuge tubes in higher capacities of 5 mL, 7 mL, and 10 mL. Prevent a common source of cross-contamination in the lab by completely eliminating the threat of mismatched caps.

These durable, polypropylene tubes are supplied sterile and are autoclavable. All tubes feature molded graduations and the 5 and 7 mL tubes have frosted marking areas. Tubes are packed in easy-to-open sterile bags of 100.

• Microtube convenience in larger capacities
• Attached caps seal at the rim with a “click”
• Sterile, easy-open bags of 100 tubes
• Molded graduations and frosted marking area

MTC™ Bio 50 mL Centrifuge Tubes

Durable, Leakproof, and Freezer-Safe for High-Speed Centrifugation.

These 50 mL centrifuge tubes are built for strength, clarity, and reliability in demanding lab environments. Manufactured from premium polypropylene, these tubes deliver excellent chemical resistance, high clarity for sample visibility, and outstanding durability during high-speed centrifugation.

Designed to withstand up to 15,000 x g RCF, these 50 mL tubes are ideal for large-volume sample prep, pelleting, and storage. The flat-top, screw-on caps ensure a secure, leakproof seal up to 95 kPa (14 psi) and provide a convenient surface for labeling.

Choose from skirted self-standing tubes (for benchtop use without a rack) or conical-bottom options for compatibility with standard tube holders and centrifuge rotors. All tubes are certified sterile and free of RNase, DNase, pyrogens, and cytotoxins. Available in bagged, racked, or Eco-Racked formats to suit any lab workflow.

Key Features

• 50 mL capacity – ideal for high-volume lab work
• Made from high-strength polypropylene
• Withstands up to 15,000 x g centrifugal force*
• Leakproof screw-cap design (95 kPa / 14 psi)
• Available in skirted (self-standing) and conical bottom formats
• Freezer-safe to -86°C
• Frosted surface for easy writing and sample identification
• Compatible with standard rotors and racks
• Sterile and certified RNase-, DNase-, pyrogen-, and cytotoxin-free 

Applications

• Large-volume centrifugation
• Cell pelleting and sample prep
• Tissue culture
• Clinical and molecular biology labs
• Sample storage and transport

*Performance specifications refer to liquids with a specific gravity of 1.0, using appropriate rotors, cushions, and adapters.