Uvitec CL-508 Crosslinker® UV Irradiation System

The Crosslinker® CL-508 is a complete, microprocessor-controlled UV irradiation system, mainly dedicated to the crosslinking of DNA and RNA by covalently binding nucleic acids to nitrocellulose or nylon membranes. With 9 possible presets for energy and time exposure, the CL-508 Crosslinker® is a safe and space-saving instrument offering fast, high-quality results. It is particularly suited for molecular biology applications requiring precise nucleic acid handling.

The system is designed for durability and long-term use, featuring a stainless-steel irradiation chamber, a protective quartz cover over the sensor, and a resistant touch-sensitive control panel. Operation is straightforward, with an intuitive interface and programmable settings.

The microprocessor-controlled system continuously monitors UV output and automatically stops irradiation once the exact programmed energy dose is reached. This ensures accuracy across every run and eliminates variability caused by fluctuations in UV lamp intensity.

With interchangeable UV tubes, the CL-508 also offers flexibility for various wavelengths, making it suitable for a wide range of applications such as Southern, Northern, dot, and slot blotting, nucleic acid crosslinking to membranes, PCR contamination reduction, RecA mutation screening, and other UV-based molecular biology techniques.

Main Attributes

• Microprocessor-controlled system for accurate and automated UV exposure
• Precise irradiation settings in energy (J/cm²) or time (seconds)
• Automatic shut-off when programmed energy dose is reached
• Highly reproducible results using integrated UV sensors
• Interchangeable UV tubes for flexible wavelength selection
• Integrated light well measurement capturing UV from all tubes for consistent readings
• Multiple safety features
• Safety interlock door with UV-blocking observation window
• Dual safety fuses
• Automatic restart with no data loss after a power interruption
• 2-Year Warranty

Programs and Controls

• 9 preset programs for UV energy exposure
• 9 preset programs for time exposure
• Preset dose of 0.120 J/cm² for optimized nucleic acid immobilization
• Manual adjustment of UV energy or exposure time
• Memory function to store last used UV setting 

Crosslinker® comes equipped with the following:

• Touch panel membrane keypad for easy operation
• Large LED display for clear readout
• No loss of information if the circuit is interrupted
• Storage of the last UV setting (energy and time)
• Internal safety interlock
• UV blocking viewing window
• Large stainless steel internal UV exposure chamber
• Removable power cable 

Climate Conditions

• Altitude: <2,000 Meters
• Operating Humidity: 20% to 80% (No concentration allowed)
• Operating Temp: 5 to 33ºC

Specifications
 

External Dimensions (D x W x H)	14.17 x 13.78 x 12 In. | 36 x 35 x 30.5 cm
Internal Dimensions (D x W x H)	12.99 x 10.24 x 5.71 In. | 33 x 26 x 14.5 cm
Weight	22.05 lb | 10 kg
Ultraviolet wavelength	254 nm, 312 nm or 365 nm
Ultraviolet Source	5 x 8-Watt Tubes
Warranty	2-Years

 
 Multiple Set Functions 
 

UV Energy Exposure	9, Preset
UV Exposure Time	9, Preset
Manual Setting of UV Energy Exposure	Min. 0.025 Joules | Max. 99.99 Joules
Manual Setting of UV Exposure Time	Min. 10 Seconds | Max. 599 Minutes
Energy Display (2 Measurement Ranges)	From 0.000 to 9.999 Joules From 00.00 to 99.99 Joules
Exposure Time Display (2 Measurement Ranges)	From 00.00 to 99.59 Minutes/Seconds From 000.0 to 599.5 Minutes/Seconds

 

• Small footprint for benchtop use
• Preset and manual controls for ultraviolet or time exposures. Preset exposure delivers 120,000 microjoules or five minutes of exposure
• Microprocessor measures and control UV output, ensuring maximum energy efficiency
• Large LED display and touch panel which displays time or energy settings
• Window on the door allows viewing of the process yet blocks out the UV radiation
• Select from models with 302nm midrange UV, 365nm longwave UV or 254nm shortwave UV Interior: 12 deep x 10 wide x 5 high inches (305 x 254 x 127mm)
• Overhead UV supplies uniform UV
• Shortwave UV model is available with choice of door (CL-1000) or drawer (CX-2000) styles
• Built-in UV sensor is calibrated at the UVP factory to ensure accuracy and reliability
• Crosslinking for attaching nucleic acids to a membrane takes seconds as compared to oven baking

CL-1000 Dimensions: Exterior: 13.7 deep x 15.6 wide x 8.75 high inches (248 x 396 x 222mm)

CX-2000 Dimensions:
Exterior: 17.5"W x 15"D x 9.75"H (445 x 381 x 248mm)
Interior: 11.4"W x 11.3"D x 3.6"H (290 x 287 x 91mm)
Depth of sample tray 11.25 Width of sample tray 11.5
Sample surface to lamp approximately 3.5 in. (89mm)

1 year warranty