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GenoSep™ Capillary Electrophoresis Systems
GenoSep™ Capillary Electrophoresis Systems
The Accuris™ GenoSep™ is a compact capillary electrophoresis system for high-resolution nucleic acid and protein characterization. The system combines automated capillary electrophoresis with sensitive fluorescence detection to deliver accurate fragment sizing, quantification, and quality assessment for DNA, RNA, proteins, NGS libraries, and cell-free DNA (cfDNA) samples.
Applications
- DNA
- RNA
- Protein Characterization
- NGS Library QC
- cfDNA Analyses
GenoSep™ Separation Technology
This instrument utilizes convenient, reusable cartridges to separate nucleic acids and proteins. Each cartridge incorporates a proprietary polymer matrix and a fused silica capillary. During analysis, programmable high voltage is applied through the capillary to generate an electric field that drives the electrophoretic migration of macromolecules through the polymer matrix. Differences in electrophoretic mobility result in size-based separation, and fluorescently labeled fragments are detected as they pass the optical detection window. User-selectable voltages enable optimization of methods for different applications and fragment size ranges.
Performance
To ensure exceptional sensitivity and reproducibility, each GenoSep™ cartridge is produced under a rigorous manufacturing process, helping to enable consistent results from cartridge to cartridge. Precision high-voltage control with automated instrument operation allows the GenoSep™ system to deliver highly reproducible migration times, enabling accurate fragment sizing and reliable comparison between runs. Consistent migration profiles provide reliable assessment of sample integrity.
The GenoSep™ system also provides exceptional sensitivity, with a limit of detection as low as 2 pg. This high sensitivity is achieved through LED-induced fluorescence detection, optimized optical design, and a proprietary low-background separation matrix that minimizes background noise and enhances signal-to-noise performance.
Software
The included Windows-based GenoSep™ software allows for instrument control and data analysis. The PC software is quick to install, set up, and begin operation.
Running an assay is simple: load the samples, select the desired method, and click Run. The software automatically controls the instrument, monitors the analysis in real time, and generates electropherograms, virtual gel images, fragment sizing info, and quantitative results.
System Specifications
| Detection Type | Fluorescence |
| Excitation Light Source | LED |
| Software Compatibility | PC (Windows 10 or Above) |
| # of Samples/Run | 1-16 |
| LOD | 0.2 pg/μL (optimized) |
| Resolution | 1 to 4 bp |
| Sample Processing Time | 3 to 5 Min./Sample |
| Sample Consumption | < 0.2 uL |
| Fragment Size CV% | ≤2% |
| Fragment Concentration CV% | ≤4% |
| Channels | Single Channel |
| Power | 110-240 V/AC, 50/60 Hz |
| Dimensions (L x W x H) | 9.3 x 11.4 x 12.2 In. | 237 x 290 x 311 mm |
| Weight | 19.14 lb | 8.7 kg |
Fragment Analysis Kits
GenoSep™ Fragment Analysis Kits provide a comprehensive range of cartridges for high-resolution analysis of DNA, RNA, and proteins. Specialized DNA kits support applications including PCR product analysis, genotyping, NGS library quality control, cfDNA analysis, and characterization of large DNA fragments. RNA and protein kits enable RNA integrity assessment, mRNA and low-input RNA analysis, as well as protein sizing across a broad molecular weight range. Each GenoSep™ cartridge delivers automated fragment analysis with accurate sizing, reliable quantification, and highly reproducible performance.
GenoSep™ Fragment Analysis Kits include a ready-to-use cartridge, size marker, alignment marker, separation buffer, dilution buffer, mineral oil, two buffer tanks, and two 0.2 mL PCR strip tubes. All consumables except the cartridge are available for purchase separately. Contact us for more information.
Kit Specifications
| Item # | Kit | Separation Range | Max. Res. | # of Sample Runs | LOD | Application |
| CE1016-DHR | GenoSep High Resolution DNA Analysis Kit | 15-5000 bp | 1-4 bp | 240 | 1 pg/uL | SSR analysis and multiplex PCR detection |
| CE1016-DSR | Standard Resolution DNA Analysis Kit | 15-5000 bp | 4-10 bp | 240 | 1 pg/uL | NGS library QC, cfDNA detection |
| CE1016-DHS | High Sensitivity Resolution DNA Analysis Kit | 15-5000 bp | 4-10 bp | 100 | 0.2 pg/uL | Low-Concentration DNA Samples |
| CE1016-DLF | Large DNA Fragment Resolution Kit | 15-165000 bp | 4-10 bp | 240 | 20 pg/uL | Large Genome Analysis, 3rd Generation Sequencing Libraries |
| CE1016-RS | Standard RNA Resolution Kit | 20-6000 nt | N/A | 100 | 5ng/uL | Total RNA, mRNA, CRISPR QC |
| CE1016-RHS | High Sensitivity RNA Analysis Kit | 20-6000 nt | N/A | 100 | 1 ng/uL | Low-Concentration RNA Samples |
| CE1016-P | Protein Analysis Kit | 5-250 kDa | N/A | 100 | 0.5 ng/uL | Protein Sample Analysis |
| SKU Number | Description | Type | Qty | Price | Quantity | Add to Cart |
| CE1016 | Electrophoresis System | 115 V | 1/ea |
24500.00
Each
|
||
| CE1016-DHR | High Res. DNA Analysis Kit | 15 to 5000 bp | 240 Runs |
497.28
Each
|
||
| CE1016-DSR | Standard Res. DNA Analysis Kit | 15 to 5000 bp | 240 Runs |
425.00
Each
|
||
| CE1016-DHS | High Sensitivity Res. DNA Analysis Kit | 15 to 5000 bp | 100 Runs |
451.20
Each
|
||
| CE1016-DLF | Large DNA Fragment Res. Kit | 15 to 165000 bp | 240 Runs |
499.00
Each
|
||
| CE1016-RS | Standard RNA Res. Kit | 20 to 6000 nt | 100 Runs |
325.20
Each
|
||
| CE1016-RHS | High Sensitivity RNA Analysis Kit | 20 to 6000 nt | 100 Runs |
399.00
Each
|
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