PR1MA™  Bacitracin

CAS Number: 1405-87-4
Molecular Weight: 1422.69
Chemical Formula: C₆₆H₁₀₃N₁₇O₁₆ S
Solubility: Water, Ethanol, and Methanol
Storage Temp: 2-8°C

Interferes with bacterial cell wall synthesis. Active against gram positive bacteria. Toxic to plant cells.

Research or further manufacturing use only, not for food or drug use.

• Appearance: White to pale buff powder
• Identification: Pass test
• pH: 5.5 - 7.5
• Loss on Drying: ≤ 5.0 %
• Residue on Ignition: ≤ 0.5 %
• Bacitracin A: ≥ 40.0 %
• SUM of bacitracin A, B1, B2 and B3: ≥ 70.0 %
• Limit of early eluting peptides: ≤ 20.0 %
• Limit of Bacitracin F: ≤ 6.0 %
• Microbial Assay (Dried Basis): ≥ 65.0 IU / mg
• Heavy Metals : ≤ 30 ppm
• Total Viable Aerobic Count: ≤ 100 CFU/g
• Particle Size (< 20 µm by volume): ≥ 99.0 %
• Crystallinity : Pass
• Appearance of Solution: Clear, colorless to slight hazy yellow
• Source: Bacillus Licheniformis
• Non Animal Origin: Non Animal Origin
• Grade: USP
• Country of Origin : Report

PR1MA™  Polymixin B Sulfate

CAS Number: 1405-20-5
Molecular Weight: 1385.61
Chemical Formula: C₅₅H₉₆N₁₆O₁₃ • 2H₂SO₄
Solubility: Water
Storage Temp: 2-8°C

Mixture of sulfates of polypeptides from certain strains of Bacillus polymixa. Active against gram negative bacteria.

Research or further manufacturing use only, not for food or drug use.

• Appearance: White to Light Yellow Powder
• Identification: Pass Test
• pH (0.5% Solution): 5.0 - 7.5
• Loss on Drying: ≤ 7.0 %
• Single Impurity: ≤ 3.0 %
• Total impurities: ≤ 17.0 %
• Bacteria Colonies: ≤ 10/g
• Ecoli Colonies: Should not be found
• Fungi and Yeast colonies: ≤ 10/g
• Assay, HPLC (on dried basis) (Sum of polymxin B1,B2, B3 and B1-1): ≥ 80.0 %
• Assay, HPLC (on dried basis) (Polymyxin B3): ≤ 6.0 %
• Assay, HPLC (on dried basis) (Polymyxin B1-1): ≤ 15.0 %
• Assay (Dried Basis): ≥ 6000 U/mg
• Assay (Wet Basis): Report U/mg
• Non Animal Origin: Non Animal Origin
• Grade: USP
• Country of Origin: Report

PR1MA™ Puromycin Dihydrochloride

CAS Number: 58-58-2
Molecular Weight: 544.43
Chemical Formula: C₂₂H₂₉N₇O₅ • 2HCl
Solubility: Water
Storage Temp: -20°C

Amino nucleoside antibiotic allows the selection of cells expressing the pac gene. Inhibits the growth of gram-positive bacteria and various animal and insect cells.

Research or further manufacturing use only, not for food or drug use.

• Appearance: White to Off White Powder
• Identification (TLC): Conforms
• Melting Point: 168 - 182 ^oC
• Purity (HPLC): ≥ 98.0 %
• Solubility: Clear, colorless or light yellow solution
• Water (KF): ≤ 12.0 %

PR1MA™  Blasticidin S Hydrochloride Powder

CAS Number: 3513-03-9
Molecular Weight: 458.9
Chemical Formula: C₁₇H₂₆N₈O₅ • HCl
Solubility: Water
Storage Temp: -20°C

• Appearance: White Powder
• Endotoxin : ≤ 1.0 EU / mg
• Identification: Pass Test
• Potency: ≥ 850 ug / mg
• Purity (HPLC): ≥ 98.0 %
• Solubility: Clear, Slightly yellow solution at 5 mg / mL in water

PR1MA™ Phleomycin, Powder

CAS Number: 11006-33-0
Molecular Weight: 1525
Chemical Formula: C₅₅H₈₅O₂₁N₂₀S ₂Cu • HCl
Solubility: Water
Storage Temp: 2-8°C

Produced by Streptomyces verticillus and part of the structurally related group of Bleomycin/Phleomycin type antibiotics. Used as a selective agent in transformation experiments with mammalian cells, plant cells, and yeast. Cytotoxic action of this type of antibiotic results from the ability to cause fragmentation of DNA. In Vitro studies indicate that Phleomycin causes the accumulation of cells in the G2 phase of the cell cycle.

Research or further manufacturing use only, not for food or drug use.

• Appearance: Light Blue Powder
• U.V. Absorbance (244nm, 600 µg/ml, 0.1cm Path): 0.20 - 0.30
• Storage Condition: Store at 2 - 8 ^oC (Very Hygroscopic: Keep container tightly sealed until ready for use).

PR1MA™ Nystatin

CAS Number: 1400-61-9
Molecular Weight: 926.1
Chemical Formula: C₄₇H₇₅NO₁₇
Solubility: DMSO
Storage Temp: 2-8°C

Polyene antifungal antibiotic produced by Streptomyces noursei.

Research or further manufacturing use only, not for food or drug use.

• Appearance: Yellow to light tan powder
• Crystallinity: Pass Test
• Identification: Pass Test
• Loss on Drying: ≤ 5.0 %
• pH @25 °C: 6.0 - 8.0
• Potency (Assay): ≥ 4400 U/mg
• Suspendability: Pass Test
• Residual Solvent (n-butanol): ≤ 1000 ppm
• Residual Solvent (Methanol): ≤ 3000 ppm
• Residual Solvent (Acetone): ≤ 5000 ppm
• Residual Solvents: The following Class 1,2, or 3 Solvents may be present in this product. All comply with the limits prescribed in the current USP.

PR1MA™  Rifampicin

CAS Number: 13292-46-1
Molecular Weight: 823.0
Chemical Formula: C₄₃H₅₈N₄O₁₂
Solubility: Dilute acid solutions
Storage Temp: 2-8°C

Interferes with synthesis of nucleic acids by inhibiting DNA dependent RNA polymerase. Active against gram positive bacteria. Less active against gram negative bacteria. Plant cell culture tested.

Research or further manufacturing use only, not for food or drug use.

• Appearance: Brownish-Red Crystalline Powder
• Crystallinity: Pass Test
• Heavy Metals : ≤ 20 ppm
• Identification: Pass Test
• Loss on Drying: ≤ 1.0 %
• pH: 4.5 - 6.5
• Purity: 97.0 - 102.0 %
• Rifampicine Quinone: ≤ 1.5 %
• Solubility: Pass
• Sulfated Ash: ≤ 0.1 %

PR1MA™ Nourseothricin Sulfate [NTC] [clonNAT] [Streptothricin Sulfate]

Common Name: [NTC] [clonNAT] [Streptothricin Sulfate]
CAS Number: 96736-11-7
Solubility: Water
Storage Temp: 2-8°C

Dihydrogen sulfate form of the weekly basic antibiotic Nourseothricin consisting of components F, E and D. Effective against gram negative and gram positive bacteria. Also effective against mycobacteria, mycoplasms, protozoa, yeasts, viruses and plants. Commonly used as a selection agent for recombinant yeast strains.

Research or further manufacturing use only, not for food or drug use.

• Appearance: White Powder
• Carbon (C): Report %
• Hydrogen (H): Report %
• Nitrogen (N): Report %
• Purity (HPLC): ≥ 85 %
• Sulfur (S): Report %

CAS Number: 1264-72-8
Molecular Weight: 2801.27
Chemical Formula: (C₅₂H₉₈N₁₆O₁₃ )₂ • 5(H₂SO₄)
Solubility: Water
Storage Temp: Short Term: 2-8°C; Long Term: -20°C

Active against gram negative bacteria. Potency approximately 20,000 units per milligram.

Research or further manufacturing use only, not for food or drug use.

• Appearance: White or almost white powder
• Arsenic (As): ≤ 2 ppm
• Heavy Metals : ≤ 20 ppm
• Identification: Conforms
• Loss on Drying: ≤ 3.5 %
• pH (1% in H₂O): 4.0 - 6.0
• Potency (Dried basis): ≥ 19000 µg/mg
• Solubility (50mg/ml in H₂O): Clear and light yellow solution
• Specific Rotation: -73 - -63 °
• Sulfate: 16.0 - 18.0 %
• Sulfated Ash: ≤ 1.0 %

PR1MA™  Spectinomycin Dihydrochloride Pentahydrate

CAS Number: 22189-32-8
Molecular Weight: 495.3
Chemical Formula: C₁₄H₂₄N₂O₇ • 2HCl • 5H₂O
Solubility: Water
Storage Temp: 2-8°C

Aminocyclitol antibiotic that inhibits protein synthesis. Cell culture tested.

Research or further manufacturing use only, not for food or drug use.

• Appearance: White or almost white, Slightly hygroscopic powder
• Identification: Pass Test
• pH @25 °C: 3.8 - 5.6
• Potency : ≥ 603 IU/mg
• Residue after Ignition: ≤ 1.0 %
• Solubility: Clear and colorless to light yellow
• Specific Rotation: +15 - +21 °
• Water (KF): 16.0 - 20.0 %

PR1MA™ Mitomycin C

CAS Number: 50-07-7
Molecular Weight: 334.3
Chemical Formula: C₁₅H₁₈N₄O₅
Solubility: Ethanol
Storage Temp: 2-8°C 

Antineoplastic antibiotic that acts as an alkylating agent after activation and also suppresses the synthesis of nucleic acids. A cell-cylce non specific agent, most active in the late G1 and early S phases.

WARNING! This product can expose you to Mitomycin-C, a chemical which is known to the State of California to cause cancer. For more information go to www.P65Warnings.ca.gov.

Research or further manufacturing use only, not for food or drug use.

• Appearance: Blue violet solid
• Identification (UV): Conforms
• Purity-HPLC (RP CH₃CN:H₂O-0-100%): ≥ 99.0 %
• Purity-HPLC (RP MEOH:H₂O-90-10): ≥ 98.0 %
• Purity-TLC (CH₂CL₂:MEOH- 9:1): ≥ 98.0 %
• Solubility (10 mg/ml MEOH): Clear Blue Solution

PR1MA™  Doxycycline Hydrochloride 

• Appearance: Yellow crystalline powder
• Absorbance (349nm): 300 - 335
• Ethanol: 4.3 - 6.0 %
• Heavy Metals : ≤ 50 ppm
• Identification (A, B, C): Pass Test
• Light Absorbing Impurities (490nm): ≤ 0.5
• pH: 2.0 - 3.0
• Potency : 800 - 920 µg/mg
• Purity: 95.0 - 102.0 %
• Related Compound (6-Epidoxycyline): ≤ 2.0 %
• Related Substance (Any Other Impurity): ≤ 0.5 %
• Specific Optical Rotation: -120 - -105 ^o
• Sulfated Ash: ≤ 0.4 %
• Water: 1.4 - 2.8 %