PrepGEM™ Universal DNA Extraction Kits

Single-tube, 15-minute DNA extraction solutions.

The PrepGEM™ Universal is a comprehensive DNA extraction kit designed for maximum yield, integrity, and ease of use. Engineered for researchers and technicians who demand efficiency and reliability, this adaptable reagent kit delivers high-quality DNA from both common and challenging sample types, all in a single tube.

Main Attributes

• Single tube simplifies processes, no transfers, no washes, no DNA loss
• Get rapid results from sample to DNA in ~15 minutes
• Broad compatibility optimized for blood, saliva, tissue, and cell culture
• Ideal for CRISPR genotyping and a wide range of downstream analyses
• Reduced plastic waste and hazardous chemicals for sustainable science

Simple and Effortless Extraction from Any Source

Consistently extract high-yield DNA from blood, saliva, tissues (including ear punches, mouse tails, and insects), and cell cultures. Our closed-tube, inhibitor-free method eliminates harsh chemical washes and multiple steps, ensuring no DNA is lost. This makes prepGEM™ Universal exceptionally powerful for low-cell-number extractions, down to a single cell.

Ideal for Advanced Genotyping and Sequencing

PrepGEM™ Universal is the perfect tool for performing confirmatory genotyping of transfected cells after CRISPR/Cas9 gene editing or preparing DNA for downstream applications. The kit produces ready-to-use DNA for STR analysis, PCR, qPCR, whole genome amplification, and amplicon sequencing.

Every Lab Deserves Rapid Results

Activate our proprietary thermophilic proteinase with a simple temperature change. The entire hands-off process is easily automated in a single tube using a standard thermocycler and takes approximately 15 minutes. Free up valuable technician time, reduce lab costs, and significantly cut down on plastic and hazardous waste.

Applications

• Blood Samples
• Liquid (fresh, EDTA, Heparin, Citrate), Swab, Stains, Storage Card (FTA)
• Saliva Samples
• Liquid, Buccal swab, Stains, Storage Card (FTA)
• Tissue Samples
• Tissue cultures, including single cell, Animal (scarpings, fat, muscle), Mouse and rat tail tips, Ear tags, Fish fins, Insects 

Kit Components

• PrepGEM™
• Histosolv
• BLUE Buffer
• RED+ Buffer
• ORANGE+ Buffer
• PDQeX Kits Include PDQeX Kit Tubes (XPU0100, XPU0500, XPU1000)