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Sealing Films

Reliable Sealing Solutions for PCR, Cell Culture, Assays, and More

Sealing film is essential for protecting samples and maintaining consistency in molecular biology and life science workflows. At MIDSCI™, we offer a complete selection of sealing films designed to prevent evaporation, reduce contamination, and protect well contents during PCR, qPCR, cell culture, incubation, storage, and thermal cycling.

Whether you’re working with petri dishes, PCR strips, flasks, bottles, or plates, our sealing solutions help ensure reliable, repeatable results. Our range includes adhesive sealing films, pierceable foil seals, heat‑sealing films, and reusable silicone sealing mats, all tested for compatibility with standard consumables and cyclers.

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PR1MA™ Extra Stretch Sealing Film

 

Flexible, airtight laboratory seal.

 

PR1MA™ Extra Stretch Sealing Film is a colorless paraffin/polyolefin film that molds to almost any surface, creating a secure seal for a wide range of laboratory containers. It adheres to test tubes, centrifuge tubes, petri dishes, flasks, bottles, and beakers, making it an essential tool for protecting sensitive samples.

 

This latex-free sealing film provides a strong yet flexible moisture barrier while allowing controlled exchange of H2O vapor, O2, and CO2, ensuring sample integrity without compromising off-gassing. Its unique formulation makes it stretchable, moldable, and self-sealing, sticking to itself or nearly any material. Ideal for use at low temperatures (including LN2 applications) and at higher temperatures, it forms an extraordinarily liquid-tight, airtight seal for dishes, tubes, glassware, and plasticware.

 

Whether you're preserving sensitive biological samples or securing vessels for transport or storage, PR1MA™ Stretch is the go-to sealing solution trusted by scientists across research, pharmaceutical, academic, and industrial laboratories.

 

Main Attributes

  • Multi-surface adaptability – Seals securely to glass, plastic, and metal surfaces
  • High stretchability – Stretches up to 350% for a snug, custom fit
  • Self-sealing – Sticks to itself and forms a tight wrap around irregular surfaces
  • Liquid-tight barrier – Ideal as an overwrap for caps, lids, and stoppers
  • Flexible and translucent – Allows for easy visual inspection of contents
  • RNase & DNase free – Safe for molecular biology applications
  • Latex-free – Suitable for sensitive lab environments
  • Cold and heat resistant – Maintains performance in a wide range of temperatures

PR1MA™ Extra Stretch Sealing Film also comes in sterile sheets.

 

When sterility matters, choose PR1MA™ Extra Stretch Sealing Film Sterile Sheets. Pre-cut in 2 x 4 In. and 4 x 4 In. sheets, these sterile seals are perfect for petri dishes, flasks, plates, and other containers. Packaged in resealable bags of 100 ready-to-use sheets, they eliminate the need for measuring or cutting.

Item#:
ASPREXSTRCHSF


PR1MA™ Sealing Mats

 

PR1MA™ 96Well PCR Sealing Mats are high-quality, reusable silicone mats designed to provide a secure, evaporation-resistant seal for 96-well PCR plates. Measuring 4.67 In. (L) x 2.90 In. (W), These mats fit standard 96-well formats and help maintain sample integrity during PCR and other laboratory workflows.

 

The pierceable silicone construction allows for easy sample access with pipette tips or needles without compromising the seal, reducing the risk of contamination or sample loss. PR1MA™ sealing mats are engineered to minimize evaporation, helping ensure consistent and reliable experimental results. Suitable for use across medical, pharmaceutical, food industry, and molecular biology applications, these sealing mats are rigorously tested and certified free of detectable RNase, DNase, DNA, and PCR inhibitors, making them ideal for sensitive molecular assays.

 

Main Attributes

  • Pierceable silicone sealing mat for convenient sample access
  • Evaporation-resistant seal to minimize sample loss
  • Compatible with standard 96well PCR plates
  • Dimensions (L x W): 4.67 x 2.90 In.
  • Suitable for medical, pharmaceutical, food, and molecular biology use
  • Certified free of RNase, DNase, DNA, and PCR inhibitors

Proudly made in the USA! Click here for more made in America products!

Item#:
ASPR1MAPCRMAT
 
Technical Drawing for PR-PCRMAT


PureAmp™ Sealing Films and Foils

 

For PCR, qPCR, ELISA, and Sample Storage.

 

PureAmp™ Sealing Films and Foils are high-quality sealing solutions designed to provide superior protection and performance for a wide range of applications, including PCR, qPCR, ELISA, and general laboratory storage. Compatible with all standard PCR plates, these films and foils ensure secure sealing with evaporation rates below 5%, helping maintain sample integrity during thermal cycling or long-term storage.

 

Choose from multiple types to meet your specific needs, including:

 

Standard adhesive pierceable aluminum foil

Standard adhesive transparent film

Optically clear standard adhesive film

Optically clear, pressure-activated non-tacky film

Low-adhesive EZ-peel film for easy removal

 

All types are available in sterile or non-sterile formats and are certified free of RNase, DNase, DNA, and PCR inhibitors, making them ideal for sensitive molecular biology workflows.

 

Key Features

  • Compatible with all standard PCR and microplate formats
  • Ideal for PCR, qPCR, ELISA, and storage applications
  • Evaporation rate maintained at < 5%
  • Certified RNase-, DNase-, DNA-, and PCR inhibitor-free

Item#:
ASPUREAMPSEALFILM

SealPlate® RollMate™ Pre-scored Film

Convenient, Easy-to-Use Roll format.

Pre-scored film on a roll is a more economical and efficient alternative to rapidly seal microplates or racked test tubes; faster than applying single sheeted film. Self-standing, non-slip supports hold the pre-scored film roll securely in place for quick and easy bench-top dispensement. The roll unwind tension can be easily adjusted to user preference. Continuous backing liner can be torn off or fed directly into a waste basket for disposal.
  • Economical
  • Quicker, more efficient sealing
  • Provides a secure seal and is easy to remove
  • Rigid polyester film features good clarity and easy handling
  • Can be used as a temporary seal while awaiting further processing
Applications
  • General laboratory use
  • Short-term storage
  • Incubation
  • ELISA
Temperature Range
  • -40°C to +120°C

Proudly made in the USA! Click here for more made in America products!

Item#:
ASFILMROLLMATE
 
SealPlate® RollMate Features
Specs SealPlate® RollMate
Sealing film selection guide by application
Sealing film selection guide by attributes

EZcap™FoilStrips

An economical and more user-friendly alternative to PCR strip caps; no sore thumbs and fingers guaranteed!

Application: PCR and light sensitive assays
Temp. Range: -20°C to +120°C

Precision cut to a smaller dimension for sealing one PCR 8-tube strip or a single row of a 96-well PCR or deep-well storage plate whenever rows must be
selectively protected or accessed. FoilStrips remove easily with no splash back as can occur with strip-caps.
  • Certified DNase- & RNase- free
  • Each sheet contains 6 strips on a continuous liner for ease of use
  • Pierceable with a pipet tip or robotic probe for direct sample recovery
  • The conformable nature of foil allows for the visual verification of the seal’s security around each well
  • 2.0 mil aluminum foil removes easily without tearing 
Helpful Tips:
  • A non-locking workstation is recommended for sample prep (e.g. 96-well round-boom plate)
  • Removal of the end-tabs at the perforations is recommended before cycling
  • A final sealing step is highly recommended in the thermal cycler because 8-tube strips flex during handling
  • Do not fold foil around sides of tubes

Proudly made in the USA! Click here for more made in America products!

Item#:
ASEZCAFOIL
 
Specs EZcapFoilStrips
Sealing film selection guide by application
Sealing film selection guide by attributes
EZcapFoilStrips Features

AlumaSeal® CS™

With a 50 uM layer of acrylic adhesive that withstands cold storage at temperatures to -80 °C.

Unlike other sealing films in the AlumaSeal® group, AlumaSeal® CS™ sealing films are not recommended for PCR or thermocycling. A single non-perforated end tab simplifies application. Simply hold the tab and strip the backing from the body of the sealing film as it lays on the plate to avoid curling. Dimensions are 82.6 by 132.6 mm, including the single 9.5 mm end tab. AlumaSeal® CS™ sealing films are certified DNase-, RNase-, and nucleic-acid-free.
  • Specially formulated for cold storage to -80 °C
  • Excellent barrier properties to retard evaporation
  • Easily pierceable with pipet tips or robotic probes for sample recovery 
*Completing application of AlumaSeal® CS™ sealing films by pressing with the accessory plate roller assures a secure uniform seal around all wells.

Proudly made in the USA! Click here for more made in America products!

Item#:
ASALUMASEL
 
AlumaSeal CS Features
Specs AlumaSeal CS
Sealing film selection guide by application
Sealing film selection guide by attributes

FoilSeal™ RollMate™ Dispenser +1 Roll of FoilSeal™ Film

500 Pre-Scored Sheets.

Pre-scored film on a roll is a more economical and efficient alternative to rapidly seal microplates; faster than applying single sheeted film. Self-standing, non-slip supports hold the pre-scored film roll securely in place for quick and easy bench-top dispensement. The roll unwind tension can be easily adjusted to user preference. Continuous backing liner can be torn off or fed directly into a wastebasket for disposal.
  • Certified DNase- & RNase- free
  • Pierceable with a pipet tip or robotic probe for direct sample recovery
  • 2.0mil aluminum foil removes easily without tearing
  • The conformable nature of foil allows for the visual verification of the seal’s security around each well
  • Not recommended for long-term cold storage
Applications
  • PCR
  • Light sensitive assays
  • Short-term storage
  • Robotics
Temp. Range
  • -20°C to +120°C
Helpful Tips
  • End-tab removal before thermal cycling is highly recommended
  • Remove diagonally from a corner to prevent tearing

Proudly made in the USA! Click here for more made in America products!

Item#:
ASFOILSEALROLLMATE
 
FoilSeal RollMate Features
Specs FoilSeal RollMate
Sealing film selection guide by application
Sealing film selection guide by attributes


ThermalSeal® 2™ and ThermalSeal® Advanced Sealing Film

ThermalSeal® 2™ and ThermalSeal® Advanced feature a soft, extra thick, conformable adhesive that forms a very strong seal around raised wells to minimize evaporation and cross-contamination.
  • Certified DNase- & RNase- free
  • Ideal for use with flat-top, semi-skirted and full-skirted PCR plates
  • Compatible with hard-shell dual component (e.g. polycarbonate/polypropylene) PCR plates
  • Large cut allows for easier positioning of the film to the plate via edge of plate alignment vs. centering
  • Available in a smaller cut for raised-rim and non-skirted PCR plates: ThermalSeal® Advanced
Application
  • PCR
Temp. Range
  • -40°C to +120°C
Helpful Tips
  • Selection of the proper film size will minimize evaporation
  • The film should not overhang or ride up the wall of a raised-rim plate
  • More complete coverage of skirted flat-top plates will reduce evaporation in the outer wells
  • End-tab removal before thermal cycling is highly recommended

Proudly made in the USA! Click here for more made in America products!

Item#:
ASTHERMSEAL2A
 
Specs ThermalSeal 2
Sealing film selection guide by application
Sealing film selection guide by attributes
ThermalSeal 2 Features

Zone-Free™ Multilayer Film

Zone-Free™ is a multilayer film consisting of a top pierceable clear polyethylene film and a white polypropylene sublayer with 96 circular areas void of adhesive.

Application: Short-term storage and robotics
 
Temp. Range: -40°C to +90°C

The white sublayer aids in the alignment of the film to the plate; alignment of opposing corner wells ensures that all 96 wells will be properly aligned. The adhesive-free zones are 9mm on center to facilitate multi-channel pipetting without adhesive fouling of pipet tips or robotic probes.
  • Pierceable
  • Offers excellent chemical resistance
  • Samples have minimal contact with adhesive due to the adhesive-free zones

Proudly made in the USA! Click here for more made in America products!

Item#:
ASZONEFREFIL
 
Sealing film selection guide by application
Sealing film selection guide by attributes
Zone-FreeFilm Features
Specs Zone-FreeFilm


ThinSeal™ Sealing Film

 

Ultra-thin, Semi-pierceable Sealing Film. Leaves minimal residue.

  • Clear polyester film usable with polystyrene or polypropylene plates
  • Marginally pierceable by single-channel pipets and probes
  • Reduces evaporation, cross-contamination and spillage
  • Removes easily and cleanly while reducing aerosols 

Temp. Range: -40°C to 120°C
 

Proudly made in the USA! Click here for more made in America products!

Item#:
ASTHINSEALSFI

ThermalSeal® Sealing Film

ThermalSeal® features a moderate strength adhesive for ease of removal.

  • Certified DNase- & RNase- free
  • Only recommended for structurally rigid polypropylene PCR plates that don’t warp
  • A less rigid polypropylene film that minimizes aerosols upon removal
  • Features good chemical resistance
Application
  • PCR
  • General storage
Temp. Range
  •  -40°C to +120°C

Proudly made in the USA! Click here for more made in America products!

Item#:
ASTHERMALSEAL
 
ThermalSeal Features
Specs ThermalSeal
Sealing film selection guide by application
Sealing film selection guide by attributes

X-Pierce™ Sealing Film

For Re-sealability and Easy Access Without Pipet Tip Coring.

X-Pierce™ film is designed for short-term processing and storage of samples that require multiple access to wells by pipet tips or robotic probes. A pre-cut “X” over each well creates bendable flaps that provide sample access without coring or adhesive fouling of tips or probes. Ideal for COVID-19 sample collection in deep-well plates using swabs.

  • Pierceable
  • Printed circles aid in the alignment of the film to the plate
  • Printed alphanumerics identify each well of a 96-well plate
  • Reseals after piercing for continued sample protection

Helpful Tips

  • To help position the film to the plate, align wells A-1 and H-12

Applications

  • Short-term processing and storage at ambient temperatures
  • Robotics

Temp. Range

  • -40°C to +90°C

Proudly made in the USA! Click here for more made in America products!

Item#:
ASFILMSONICATION
 
X-PierceSealing Films Features
Specs X-PierceSealing Films
Sealing film selection guide by application
Sealing film selection guide by attributes
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